Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology

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R. Wayne Albers, Donald L. Price
Academic Press, 2 nov. 2011 - 1120 pagini

Basic Neurochemistry, Eighth Edition, is the updated version of the outstanding and comprehensive classic text on neurochemistry. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences.

The text has evolved, as intended, with the science. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from intracellular trafficking, stem cells, adult neurogenesis, regeneration, and lipid messengers. It contains expanded coverage of all major neurodegenerative and psychiatric disorders, including the neurochemistry of addiction, pain, and hearing and balance; the neurobiology of learning and memory; sleep; myelin structure, development, and disease; autism; and neuroimmunology.

  • Completely updated text with new authors and material, and many entirely new chapters
  • Over 400 fully revised figures in splendid color
  • 61 chapters covering the range of cellular, molecular and medical neuroscience
  • Translational science boxes emphasizing the connections between basic and clinical neuroscience
  • Companion website at http://elsevierdirect.com/companions/9780123749475
 

Cuprins

II INTERCELLULAR SIGNALING
233
III INTRACELLULAR SIGNALING
409
IV GROWTH DEVELOPMENT AND DIFFERENTIATION
531
V CELL INJURY AND INFLAMMATION
595
VI INHERITED AND NEURODEGENERATIVE DISEASES
677
VII SENSORY TRANSDUCTION
887
VIII NEURAL PROCESSING AND BEHAVIOR
943
Glossary
1057
Index
1063
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Despre autor (2011)

Scott Brady is Head of the Department of Anatomy and Cell Biology at University of Illinois, Chicago, Illinois, USAUniversity of Illinois, Chicago, IL, USA.

George Siegel is Emeritus Professor of Neruology at Loyola University Chicago Stritch School of Medicine; Chief of Neurology Service (retired), Edward Hines, Jr. Veterans Affairs Hospital, Chicago, IL, USA.

OBITUARY FOR R. WAYNE ALBERS, August 5, 1928 - September 28, 2013R. Wayne Albers, Ph.D., Scientist Emeritus, Chief of Section on Enzyme Chemistry (retired), Laboratory of Neurochemistry in the NINDS, NIH, Bethesda, MD, is a world-recognized neuroscientist most noted for his research in the field of membrane cation transport and neuronal excitability in the nervous system. Dr. Albers and physiologist R.L. Post performed the principal experiments leading to their now widely-held Albers-Post model for the mechanism of the cation transport enzyme, sodium-potassium-activated ATPase. Dr. Albers was one of the founding co-editors of the comprehensive text, Basic Neurochemistry: Molecular, Cellular and Medical Aspects, first published in 1972, continuing as co-editor for 8 editions, the latest having been published in 2012. After receiving his PhD at Washington University School of Medicine in 1954, Dr. Albers embarked on a distinguished career of research at the NIH, being a founding investigator in the first Laboratory of Neurochemistry.Dr. Albers was one of the first members of the American Society for Neurochemistry at its inception, serving on its Council and its Committees on Publications and Education and on Electronic Publications. He has served as Professor of Biochemistry at George Washington University, Faculty Member of the NIH Foundation for Advanced Education in the Sciences, Associate Editor of the Journal of Neurochemistry and of Experimental Neurology, and on the editorial boards of several journals.Dr. Albers passed away on September 28, 2013. He was 85 years old and is survived by his former wife, Frances Albers, their children Gail Morrell, Belinda Caron and Patricia Steinhoff, 6 grandchildren, and 8 great-grandchildren. He also had a son, the late Jonathan Albers.Dr. Albers was considered a gentleman, an excellent scientific colleague with a keen intellect and friend by all who worked with him. He will be sorely missed, not only by his family, but also by the entire neurochemistry community.George J. SiegelOctober 1, 2013

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