Genes and Signal Transduction in Multistage Carcinogenesis

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CRC Press, 21 dec. 1988 - 480 pagini
This book describes the identification and characterization of genetic loci that determine susceptibility to liver, mammary, or skin carcinogenesis in rodents. It focuses on protein kinases and phospholipases, and stress-related signal transduction.
 

Cuprins

Genetic Control of Hepatocarcinogenesis in Inbred Mice
3
Contents
6
Modulation of Mammary Carcinogenesis by Enhancer
19
Genetic Determinants of Susceptibility to Mouse Skin Tumor
39
Suppression and Expression of the Transformed Phenotype
69
Genetic Analysis of Transformation by the src Oncogene
91
Genes and Signals Involved in Tumor PromoterInduced
139
Regulation of Gene Expression by the Tumor Promoter 120
167
Regulation of Human Papillomavirus Gene Expression
231
Structural Definition
263
Role of Protein Kinase C in Stimulation of Interleukin 2 Production
279
Lipocortins a Family of Phospholipase A2Inhibitory Proteins
309
Role of raf and myc Oncogenes in Signal Transduction
339
fos and the ImmediateEarly Response in the Central Nervous
377
Free Radicals and Signal Transduction in Tumor Promotion
391
cis and transActing Genetic Elements Responsible for Induction
415

Gene Activation During Multistage Carcinogenesis in Mouse Skin
191
Tumor Promotion by 2378Tetrachlorodibenzopdioxin
207
Genes That Confer Susceptibility to Neoplastic Transformation
221
Structure Function Analysis of fos Protein
441
Index
457
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