Primary Liver Tumors: Proceedings of the 25th Falk Symposium, on the Occasion of the 5th Centennial Celebrations of the Eberhard-Karls-Universität Tübingen Held at the Schwartzwaldhotel Titisee, West Germany, October 3-5, 1977University Park Press, 1978 - 511 pagini |
Cuprins
the Increasing Importance of Liver Tumors | 3 |
Hepatocarcinogens as Potential Risk for Human Liver | 11 |
Metabolism of Carcinogens Its Significance for | 31 |
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acid activity adenoma aflatoxin alkylation alterations animals antigen appear areas associated benzo(a)pyrene binding Biochem Cancer Res carcinogenesis carcinogens cause cellular changes chemical chronic cirrhosis compared compounds concentrations containing contraceptives cytoplasmic dieldrin disease dose drugs early effect enzyme epoxide evidence experimental experiments exposure factors Figure findings foci formation forms given glycogen growth hepatic hepatocellular carcinoma hepatocytes hepatoma human hyperplasia important incidence increased indicate induced initial lesions levels liver cancer liver cell liver tumors male malignant mechanism metabolism metabolites mice microsomal months mutagenic nodular nodules normal observed occur oral organs oxide Pathol patients population positive possible present primary primary liver produced proliferation protein rat liver rats reaction recently reported serum shown similar single species stage structures suggest Table thorotrast tissue transformation treatment tumors various vinyl chloride weeks